Omega-3 fatty acids are essential nutrients that are anti-inflammatory and important for brain and heart health. They have the most research of all fatty acids in connection to autism. Certain studies show a variety of improvements including social interaction, repetitive and restricted interests, behaviors, stereotypy, lethargy, improved nonverbal intellectual ability, restlessness, agitation, irritability, and self-injurious behaviors.

Omega-6 is an essential fatty acid involved in cell membrane structure and activity, as well as brain development. Due to the fact that many foods contain both omega-6 and omega-3 together, it can be challenging to associate the effects of omega-6 alone in research studies. Focusing on the omega-6 ratio of the diet by emphasizing alternative fat sources is key.